Unfortunately, Vista does feel to some extent like ME in terms of some features really being badly implemented and of course the hardware/performance issues.
But I have found that on the bright side, it does have advantages to XP if used by non-tech-savvy friends and family - I noticed a lot less unwanted maintenance is required due to the improved security.
Overall, my biggest grudge is that 1) it hasn't improved my productivity as a developer one bit and 2) that the search facility it ships with is fundamentally broken.