DISQUS

I think Drobos are awesome, but they're really too expensive for what they do. Online backups are a great idea because you lose nothing if your house catches on fire or someone robs you, but in my opinion they cost too much as well.

Personally, I use my webhost as a backup for really important stuff that I would feel crushed if I lost, photos or my family, important documents, etc. I also use a cheap Ubuntu box for almost everything I have. I use rsync to automate everything. It's free if you've got extra parts, or for the price of a Drobo (or less!), you've got a second computer that you can do tons of stuff with.
The stuff that I don't keep backed up to my host I keep a list of with an automated bash script, so if I lose my music for instance, I've got a list of what to redownload.