For me, it's not just spam messages or spam profiles that could start affecting the 'cleanliness' of Facebook. I feel that newsfeed items about applications and applications requests are just as irritating as any spam. When the enslaught of applications began, what first struck me was how they completely detracted from that was the initial attraction of Facebook - seeing snippet after snippet of news about what your friends were doing (who they'd made friends with, what their status was and what photos they'd been tagged in, etc). I love gossip, so a newsfeed full of these details was heaven for me. When the newsfeed started getting filled up with 'news' about applications, the gossip-worthy nature of the site became diluted. I'm very anti-applications and it's something I've mentioned a few times in my blog here - http://somethingclosetonothing.blogspot.com/