Hello!
The comments on this profile are unclaimed and thus are unverified.
Do they belong to you? Claim these comments.
cariaso
Is this you? Claim Profile »
10 months ago
in Your personal health: 23andme v2 on bbgm - the discussion
"Our scientists spent many months sifting through scientific journals and online databases to select new SNPs". 23andMe's original chip was an Illumina550 plus additional custom content. This chip may be based on the 1M chip, but if it were only that they would have lost some of their existing advantage over deCODEme. I won't be surprised to find that all of SNPedia (from before a certain date) is part of the new content.
1 reply
1 year ago
in Just Downloaded a File Containing my Raw Genome Data. Now What? on BUZZYEAH
I have gotten the results back. The first thing I should mention is that while I greatly appreciate people who are so open with their genome, I didn't actually upload my own data, I uploaded data from 23andMe's Greg Mendel profile. The company behind this effort is Genseq which is based in Malaysia. There appears to be 24 public user profiles on the site, Although a few of those appear to be dupicates or test users. I'll be curious to hear if anyone can see the 'cariaso' profile, since I've done nothing to share it. A lot of the site emphasis seems to be on creating family trees linked to a manually entered medical history.
The UI is a little rough, but functional. Some of the artwork is quite good, but the look&feel of the dynamic elements isn't nearly as pretty. There are several visualizations, a relative risk which does not seem to render for me, a sized/colored ATCG (which seems a poor choice for what I think it wants to convey) as well as a 'visible human' style map which responds to mouse-overs and clicks. The last element is particularly well done, but seems more eye candy than scientific rigor. Notably visualizations in one of the main windows disappears when elements are moved outside the bounding box.
They appear to track 22 medical conditions which are classified as either high or low confidence, and for each there is a red/yellow/green high/med/low risk assignment. These also provide a % risk for european/asian/african populations vs 'my' data. Generally the site does link to pubmed, to backup the claims. I find the lack of an rs# makes it difficult to verify specific claims, but that is partly my bias showing through.
It all seems reasonable enough, but I'm not exactly overwhelmed. In fairness I've got a certain bias due to promethease, which is often similarly criticized.
The UI is a little rough, but functional. Some of the artwork is quite good, but the look&feel of the dynamic elements isn't nearly as pretty. There are several visualizations, a relative risk which does not seem to render for me, a sized/colored ATCG (which seems a poor choice for what I think it wants to convey) as well as a 'visible human' style map which responds to mouse-overs and clicks. The last element is particularly well done, but seems more eye candy than scientific rigor. Notably visualizations in one of the main windows disappears when elements are moved outside the bounding box.
They appear to track 22 medical conditions which are classified as either high or low confidence, and for each there is a red/yellow/green high/med/low risk assignment. These also provide a % risk for european/asian/african populations vs 'my' data. Generally the site does link to pubmed, to backup the claims. I find the lack of an rs# makes it difficult to verify specific claims, but that is partly my bias showing through.
It all seems reasonable enough, but I'm not exactly overwhelmed. In fairness I've got a certain bias due to promethease, which is often similarly criticized.
1 reply
Andrew Meyer
Mike, thanks for excellent comment. This really helps as MyFamilyHealth doesn't provide much of a service preview.
I'm thinking I'll stick to playing w/ Promethease for now.
Btw: I didn't run across your profile in the community section.
I'm thinking I'll stick to playing w/ Promethease for now.
Btw: I didn't run across your profile in the community section.
1 year ago
in Just Downloaded a File Containing my Raw Genome Data. Now What? on BUZZYEAH
I've registered and uploaded a genetic profile. It wasn't clear until after the upload, but I now see the message:
"Hi ,
Upload your data here and in a few weeks you can analyse your data usingMyFamilyHealth tools and services for FREE! "
Since the upload also had a text box labeled:
"Please tell us some detail of your data, such as:
i. From where did you acquire this data.
ii. The data format or specification.
iii. Any related details. "
It would seem likely a human (mayhap swswsu) will read that file and do your analysis.
"Hi ,
Upload your data here and in a few weeks you can analyse your data usingMyFamilyHealth tools and services for FREE! "
Since the upload also had a text box labeled:
"Please tell us some detail of your data, such as:
i. From where did you acquire this data.
ii. The data format or specification.
iii. Any related details. "
It would seem likely a human (mayhap swswsu) will read that file and do your analysis.
1 reply
Andrew Meyer
Interesting. I'll probably upload my 23andMe file and see what they can tell me.
Mike, have you gotten your MyFamilyHealth results back yet?
Mike, have you gotten your MyFamilyHealth results back yet?
From what I had heard, custom content was a key part of the value proposition, so I doubt if you're presumption is incorrect. After reading their website, I am not sure they've upgraded to the 1M yet.
Also very interesting in seeing what kind of algos/analytical engine they are providing or using at the back end, more that the white papers available at this point.